MICROBIOLOGICAL QUALITY CONTROL OF A NEW PLANTS MIX EXTRACT FOR VETERINARY USE

Published in Scientific Bulletin. Series F. Biotechnologies, Vol. XXI
Written by Tomina PURCARU, Camelia DIGUŢĂ, Florentina MATEI

The microbiological control of veterinary products needs an integrated approach, being part of the quality assurance in the pharmaceutical industry. During the production of a phytopharmaceutical product of veterinary use it is compulsory to have a standardized method for the quantification of the microbial charges (fungi and bacteria) from the raw vegetal material to the final product. Our work has been focused on the microbial charges of a new phytoimmunomodulator veterinary product based on Inula sp., Eupatorium sp. and Helleborus sp. For the product standardisation several attempts have been done and one part of the work was related to microbiological criteria fulfilment. The microbial charges have been quantified according to adapted method developed by the authors and correlated to limits recommended by European Pharmacopeia. In the case of the raw dried and grounded plants the total mesophilic aerobe bacteria load is much higher than the recommended limits, while the fungal load has reached almost the maximum recommended limits. Acceptable contents of coliforms and no traces of Salmonella have been detected in the final product. The phytopharmaceutical company to patent and produce the new veterinary product, should make efforts especially in the raw material procurements, as long as their actual sources comes with a much more higher content in aerobe bacteria than the recommended limits. Supplementary measures should be taken to avoid in this context the cross-contamination.

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PURCARU T., DIGUŢĂ C., MATEI F. 2017, MICROBIOLOGICAL QUALITY CONTROL OF A NEW PLANTS MIX EXTRACT FOR VETERINARY USE. Scientific Bulletin. Series F. Biotechnologies, Vol. XXI, ISSN 2285-1364, 115-120.


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