ISSN 2285-1364, ISSN CD-ROM 2285-5521, ISSN ONLINE 2285-1372, ISSN-L 2285-1364


Published in Scientific Bulletin. Series F. Biotechnologies, Vol. XXIV, Issue 2
Written by Madiha ABD EL-HAY

Chia and quinoa seeds considered as a powerful medicinal plants and an excellent dietary source of bioactive constituents i.e. flavonoids and phenolic compounds and plenty of omega-3 and omega-6 fatty acids, I hypothesize that chia and quinoa seeds powder and extracts may have a role in lowering lipid accumulation in non-alcoholic fatty liverinduced by high fat high fructose diet. Thirty-six male rats were randomly divided into 6 dietary groups, containing 6 rats in each; normal control group, high fat high fructose diet (HFHFrD) control group, HFHFrD with CS powder 10 g/kg (BW), HFHFrD with QS powder10 g/kg (BW), HFHFrD with CS extract 50 mg/kg (BW), HFHFrD with QS extract 50 mg/kg (BW). After 8 weeks, it was revealed that the consumption of CS & QS extracts were found to normalize many indicators which were shifted to pathological values as a consequence of HFHFrD-induced nonalcoholic fatty liver disorders: there was a significant increase in HDL-C and a significant decrease in total cholesterol, TG, LDL-C and VLDL-C. In addition, level of lipids peroxidation (LP) was reduced as compared to HFHFrD normal group. Thus, these observations suggest that chia and quinoa seeds are potential agents on management of fat accumulation in nonalcoholic fatty liver rats.

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