Published in Scientific Bulletin. Series F. Biotechnologies, Vol. XXIII
Written by Alice GRIGORE, Svetlana COLCERU-MIHUL, Corina BUBUEANU, Lucia PÎRVU, Cristina BAZDOACĂ, Sultana NIŢĂ
The aim of this study was to obtain selective fractions of Hyssopus officinalis L. by different methods and to investigate a possible correlation between their chemical content and antioxidant activity in order to establish a potential effect of this species on counteracting diseases associated with aging processes. HPLC analysis and quantitative determination of active principles from nine selective fractions show that the values were well correlated with the ones resulted by spectrophotometrically methods. The selective fractions have a total flavonoid content expressed as rutin from 1.236 to 19.060 % and respectively 0.126 to 16.783% polyphenolcarboxylic acids expressed as rosmarinic acid. It has been observed that the fractions with high content in polyphenolcarboxylic acids and flavonosides exhibit maximum antioxidant activity. There are selective fractions containing only one of the classes of compounds (flavonosides or polyphenolcarboxylic acids) in a higher amount that show great antioxidant activity. A strictly correlation between the flavones content of the selective fractions and antioxidant activity can not be made by this method.
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