Published in Scientific Bulletin. Series F. Biotechnologies, Vol. XXVI, Issue 2
Written by Mohammed Shaymaa Omar MOHAMMED, Narcisa BABEANU, Călina Petruţa CORNEA, Nicoleta RADU
Limonene is a biomolecule that can be easily obtained from plant sources with remarkable biological effects. It is found in large quantities in citrus essential oils (concentrations up to 98%) and in moderate amounts in essential oils obtained from various species of geranium. The article presents the reasons why this compound may have potential uses in regenerative medicine, especially in dermatological applications, where these compounds or formulations which contain this compound, alone or via intermediary products which result from metabolization (such as perillyl alcohol) can accelerate wound healing, inhibit skin tumors development, or inhibit pathogenic microorganisms such as Staphylococcus aureus or Pseudomonas aeruginosa. Studies performed in vivo, on healthy persons who have tested in time the skin cleaning products which contain limonene or essential oils with limonene, were confirming that the products with Limonene do not give perturbation to normal skin microbiota. These data recommend Limonene as a potential candidate for regenerative medicine applications in the field of dermatology.
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