Published in Scientific Bulletin. Series F. Biotechnologies, Vol. XXIX, Issue 1
Written by Fawzia SHAAT, Ramona-Daniela PAVALOIU, Ciprian FODOR, Emilian ROMAN, Mariana FODOR
Liposomes play a vital role in the advancement of regenerative cosmetics due to their capacity to encapsulate, protect, and effectively deliver active ingredients deep within the skin. These versatile carriers mimic biological membranes, enhancing the stability and bioavailability of sensitive compounds such as peptides, growth factors, vitamins, and plant-derived bioactives. Regenerative cosmetics leverage liposomal systems to promote skin repair, boost collagen synthesis, and combat signs of aging by targeting cellular pathways with precision. This review explores the state-of-the-art advancements in liposome technology for cosmetic applications, emphasizing their role in addressing challenges such as poor solubility, rapid degradation, and limited penetration of active agents. Additionally, we examine the economic viability, scalability, and regulatory considerations associated with integrating liposome-based products into the commercial cosmetic market. Despite their transformative potential, challenges remain in ensuring formulation stability, achieving cost-effective production, and verifying long-term safety. By providing a comprehensive overview, this review underscores the potential of liposome technology to revolutionize regenerative cosmetics, paving the way for next-generation skincare innovations that restore, rejuvenate, and protect the skin.
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